Marine microfossils (dinoflagellate cysts and planktonic foraminifera) and geochemical (XRF-Ti/Ca)-based climatic records from a core located off the Fleuve Manche (FM) paleo-mouth (MD13-3438) have revealed that sustained warm summer sea surface temperatures (SSTs) during sub-millennial climate changes within HS1 (~18–14.7 ka) may have played a key role in the FM regime related to the European Ice Sheet (EIS) melting rate. In this study, we have analyzed the MD13-3438 pollen content over the HS1 at a mean resolution of ~50 years to test whether vegetation-based air temperatures were coupled to SSTs face to this rapid climate variability. First, our results highlight two major phases of pollen sources at site MD13-3438, preventing the pollen record to be interpreted as a continuous record of the evolution of vegetation and climate occupying a single watershed across HS1. The first phase, i.e. the HS1-a interval (~18–16.8 ka), is marked by strong occurrences of boreal pollen taxa (especially Picea-Abies). Considering their spatial distribution and the coalescence of the British and Scandinavian ice sheets into the North Sea during the Last Glacial Maximum, these taxa probably originated from the North European Plain, i.e., eastern FM tributaries (east of the Rhine River), where cool-humid conditions generally prevailed. Then, the second phase, i.e. the HS1-b interval (~16.8–14.7 ka BP), is characterized by a deceleration of the EIS retreat and the drop of boreal pollen values at site MD13-3438 further signing a less influence of the upstream FM drainage system and thus a better characterization of pollen sources related with western FM tributaries. Superimposed to these two HS1 main phases, pollen fluctuations are concomitant with sub-millennial variability in the EIS deglaciation intensity. During the early HS1 (HS1-a), we discussed two short-term increases in the ratio between deciduous trees (Quercus-Corylus-Alnus) and herbaceous plants (Plantago-Amaranthaceae-Artemisia). These events were coeval with phases of increasing FM meltwater runoff and SST seasonality (i.e., dinocyst-based summer SST amplification). We associated these events with lower contribution of the upstream FM catchment as well as, possibly, atmospheric warming and regional sea-level positive oscillations. The HS1-b is composed of three main phases that appear more influenced by the downstream FM drainage system. HS1-b1 (16.8–16.3 ka BP) corresponds to the driest and coldest conditions west of the Rhine River. HS1-b2 (16.3–15.6 ka BP) is coeval with large arrivals of iceberg from the Hudson strait in the Bay of Biscay and thus likely to a major sea-level positive oscillation associated with a phase of FM valley reworking. HS1-b3 (15.6–14.7 ka BP) corresponds to persistent arid conditions that preceded the subsequent more humid conditions recorded from 14.7 ka BP at the start of the Bölling-Alleröd.